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Despite progress, smoking and exposure to secondhand smoke are responsible for more than 480,000 premature deaths annually and more than $300 billion in health care expenses and other economic costs each year

Best practices and the way forward Cessation services should be sustainably funded as part of all comprehensive tobacco control programmes, integrated into health services and required to be covered by government and private health insurance schemes

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In vitro studies of different nicotine products are required to better understand the inflammatory profile and underlying mechanisms of mucosal lesions

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